17-HYDROXY-17-PENTAFLUOROETHYL-ESTRA-4,9(10)-DIEN-11-ARYL DERIVATIVE, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES

• Main Authors: WOLFGANG SCHWEDE, ANDREA ROTGERI, CARSTEN MOLLER, ULRICH KLAR, WILHELM BONE
• Format: Patent
• Language: English; Japanese
• Published: 15.06.2017
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; STEROIDS

PROBLEM TO BE SOLVED: To produce highly potent competitive progesterone receptor antagonists available and thus provide alternatives for the treatment of gynaecological diseases.SOLUTION: The present invention provides compounds of formula (I), or separate stereoisomers of the compounds, salts of the compounds, solvates of the compounds or solvates of the salts (including all crystal forms thereof).SELECTED DRAWING: None 【課題】利用可能な非常に強力な競合的プロゲステロン受容体拮抗薬を製造すること、つまり婦人科疾患を治療するための代替品の提供。【解決手段】式（I）で表される化合物或いは、その化合物の分離された立体異性体、その化合物の塩、その化合物の溶媒和物、又は前記塩の溶媒和物（ただしその中に、これらの物のあらゆる結晶形態が含まれる）。【選択図】なし