SUSTAINED-RELEASE GRANULES

PROBLEM TO BE SOLVED: To provide granules having a zero-order release profile.SOLUTION: The present invention provides an oral granule having a drug zero-order release profile, wherein drug powder particles are dispersed in a matrix consisting of hydroxypropyl methylcellulose and polyglycerol fatty...

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Bibliographic Details
Main Authors NAKAMURA TATSUO, KUSHIOKA TAKUYA
Format Patent
LanguageEnglish
Japanese
Published 18.05.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide granules having a zero-order release profile.SOLUTION: The present invention provides an oral granule having a drug zero-order release profile, wherein drug powder particles are dispersed in a matrix consisting of hydroxypropyl methylcellulose and polyglycerol fatty acid ester.SELECTED DRAWING: Figure 3 【課題】０次放出プロファイルを有する顆粒剤を提供すること。【解決手段】顆粒中にヒドロキシプロピルメチルセルロースとポリグリセリン脂肪酸エステルからなるマトリックス中に薬剤の粉末粒子が分散しており、薬剤の０次放出プロファイルを有する経口用顆粒剤。【選択図】図３
Bibliography:Application Number: JP20160025038