APOPTOSIS INDUCING AGENTS FOR TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

• Main Authors: GEORGE DOHERTY, GERARD SULLIVAN, TAO ZHI-FU, STEVEN ELMORE, SONG XIAOHONG, LAURA HEXAMER, AARON R KUNZER, LE WANG, MICHAEL WENDT, LISA HASVOLD, XILU WANG, TODD M HANSEN, ROBERT MANTEI, ANDREW J SOUERS, DING HONG, GARY T WANG, MILAN BRUNCKO
• Format: Patent
• Language: English; Japanese
• Published: 09.03.2017
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, and compositions containing the compounds.SOLUTION: The present invention provides a compound represented by formula (II) and the like.SELECTED DRAWING: None 【課題】抗アポトーシスＢｃｌ−２タンパク質の活性を阻害する化合物、その化合物を含む組成物の提供。【解決手段】式（ＩＩ）等で表される化合物。【選択図】なし