CELL SORTING APPARATUS

• Main Authors: MASUDA YASUSUKE, SAKUMA SHINYA, MAENO TAKANORI, ISOZAKI AKIHIRO, ARAI FUMITO, AIDA KEISUKE, KAWAI TAKAYUKI, HAYAKAWA TAKESHI, TANAKA YO, NOZAWA TAISUKE, YALIKUN YAXIAER, HOSOKAWA YOICHIRO, IINO TAKANORI
• Format: Patent
• Language: English; Japanese
• Published: 02.03.2017
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; SPIRITS; TESTING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide a cell sorting apparatus capable of sorting target cells more reliably and more efficiently.SOLUTION: The present invention provides a cell sorting apparatus comprising: a substrate; a flow path 12 having a cell-sorting region 13 having one surface being opened as an open surface through which a liquid containing a cell line 16 of cells 15 aligned one by one in the direction of flow flows from the upstream to the downstream; a first pressure wave-imparting mechanism for imparting a pressure wave 20 to the liquid 14 in the cell-sorting region 13 in the direction from the opposite side of the opening surface to the opening surface to separate a first target cell 15a from the cell line 16 and move the same toward the open surface; and a first liquid collection tank 24 disposed on the open surface side of the cell sorting region 13 and receiving droplets of the liquid containing the first target cells 15a.SELECTED DRAWING: Figure 2 【課題】より確実に、より効率よく標的細胞を分取することが可能な細胞分取装置を提供する。【解決手段】基板と、前記基板に形成され、流れ方向に沿って細胞１５が１つずつ並んだ細胞列１６を含む液体が上流から下流に向けて流通し、一面が開放した開放面を備えた細胞分取領域１３を有する流路１２と、前記細胞分取領域１３の前記液体１４に、前記開放面の逆側から前記開放面に向けた圧力波２０を与え、第１の標的細胞１５ａを前記細胞列１６から分離して前記開放面に向けて移動させる第１の圧力波付与機構と、前記細胞分取領域１３の前記開放面側に配置され、前記第１の標的細胞１５ａを含む液滴を受け取る第１の収液槽２４とを備えることを特徴とする。【選択図】図２