PHARMACEUTICAL COMPOSITIONS COMPRISING S1P MODULATOR

• Main Authors: COLLEEN RUEGGER, VALAZZA STEPHEN, AMBUEHL MICHAEL, BEYER JUTTA, CARRENO-GOMEZ BEGONA
• Format: Patent
• Language: English; Japanese
• Published: 16.02.2017
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition comprising a sphingosine-1 phosphate (S1P) receptor modulator, in particular a sphingosine-1 phosphate receptor agonist.SOLUTION: The present invention provides a solid pharmaceutical composition suitable for oral administration, comprising a sphingosine-1 phosphate receptor modulator, and a microcrystalline cellulose, in the absence of a sugar alcohol. The composition is used for treating a subject in need of immunosuppression.SELECTED DRAWING: None 【課題】スフィンゴシン−１ホスフェート（Ｓ１Ｐ）受容体調節剤、とりわけスフィンゴシン−１ホスフェート受容体アゴニストを含む医薬組成物の提供。【解決手段】経口投与に適した固体医薬組成物であって、スフィンゴシン−１ホスフェート受容体調節剤および微結晶セルロースを含み、糖アルコールを含まない組成物。免疫抑制を必要とする対象を処置するための該組成物。【選択図】なし