PROSTAGLANDIN-CONTAINING LIPID MICROSPHERE

PROBLEM TO BE SOLVED: To provide a lipid microsphere which has increased stability of prostaglandin, high transparency, excellent emulsification stability, and a long shelf life.SOLUTION: The invention provides a prostaglandin-containing lipid microsphere wherein prostanoid, an oil component, lecith...

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Bibliographic Details
Main Authors NAGATA KOZO, IZUMI YASUYUKI, TANISAKA HIROKI, TSUJIHATA SHIGENORI
Format Patent
LanguageEnglish
Japanese
Published 26.05.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a lipid microsphere which has increased stability of prostaglandin, high transparency, excellent emulsification stability, and a long shelf life.SOLUTION: The invention provides a prostaglandin-containing lipid microsphere wherein prostanoid, an oil component, lecithin, and water are contained, the content of the lecithin is 500-5000 mass times of the content of the prostanoid, the content of the lecithin is 0.5-10 mass times of the content of the oil component, and the content of a higher fatty acid is 0.06 mass times or less of the content of the lecithin.SELECTED DRAWING: None 【課題】プロスタグランジンの安定性を向上させ、透明性が高く、かつ乳化安定性に優れた保存期限の長い脂肪乳剤を提供する。【解決手段】プロスタグランジン類、油成分、レシチン、及び水を含む脂肪乳剤であって、前記レシチンの含有量が前記プロスタグランジン類の含有量の５００〜５０００質量倍であり、前記レシチンの含有量が前記油成分の含有量の０．５〜１０質量倍であり、かつ高級脂肪酸の含有量が前記レシチンの含有量の０．０６質量倍以下であることを特徴とする、プロスタグランジン含有脂肪乳剤。【選択図】なし
Bibliography:Application Number: JP20160025949