W/O/W TYPE EMULSION

• Main Authors: IMAI YOKO, TAJIMA KAZUO, YANAE KOJI, SANO SHOKO
• Format: Patent
• Language: English; Japanese
• Published: 23.05.2016
• Subjects: CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR RELEVANT APPARATUS; TRANSPORTING

PROBLEM TO BE SOLVED: To provide a novel W/O/W type emulsion for stabilizing piceatannol which is contained in passion fruit seed extract, has ultraviolet damage effect and MMP-2 inhibiting action, and has a strong acid region at pH 2.0 or less or is unstable at pH 5.0 or more, and to provide a production method thereof.SOLUTION: The invention provides a W/O/W type emulsion comprising an internal aqueous phase containing polyphenol, such as piceatannol, an oil phase surrounding the internal aqueous phase, and an external aqueous phase surrounding the oil phase; wherein a first closed endoplasmic reticulum formed by a first amphiphile, such as triolein acid penta glyceryl, intervenes in an interface of the internal aqueous phase and the oil phase, and particles of polycondensation polymer having a second closed endoplasmic reticulum formed by a second amphiphile, or a hydroxyl group intervenes in the external interface of the oil phase and the external aqueous phase.SELECTED DRAWING: None 【課題】パッションフルーツの種子抽出物に含まれ、紫外線ダメージ効果やＭＭＰ−２の阻害作用を持つピセアタンノールがｐＨ２．０以下で強酸性領域若しくは５．０以上で不安定であるため、安定化するための新規なＷ／Ｏ／Ｗ型エマルション及びその製造方法の提供。【解決手段】ピセアタンノール等のポリフェノールを含有する内水相と、内水相を囲繞する油相と、油相を囲繞する外水相と、を含んで構成され、内水相と油相の界面にトリオレイン酸ペンタグリセリル等の第１の両親媒性物質によって形成される第１の閉鎖小胞体が介在し、油相と外水相の外界面に第２の両親媒性物質によって形成される第２の閉鎖小胞体または水酸基を有する重縮合ポリマーの粒子が介在する、Ｗ／Ｏ／Ｗ型エマルション。【選択図】なし