FORMED SHEET AND HEMOSTATIC MATERIAL

• Main Authors: KANEKO HIROAKI, KAGEYAMA YUKAKO, KAWAMURA RYOICHI, YAMAGUCHI AYUKO, ONO AKITO, SATAKE MAKOTO, IMAMURA TAKAYUKI, AKIYAMA YUSUKE, HONDA SUSUMU, FUJINAGA KENTARO, HIRASHIMA MASAKI
• Format: Patent
• Language: English; Japanese
• Published: 12.05.2016
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL

PROBLEM TO BE SOLVED: To provide a formed sheet that has a good supportability and leachability for hemostatic protein, i.e. fibrinogen and/or thrombin, and has a good flexibility (tissue followability), and thus excellent in hemostatic.SOLUTION: Provided is: a formed sheet of a polymer composition containing one or more protein selected from fibrinogen or thrombin, and one or more polymer selected from aliphatic polyester and water-soluble polymer; and a laminated formed sheet in which the formed sheet is a formed film or a formed fiber, or/and a laminated formed sheet including a first polymer composition layer comprising fibrinogen and water-soluble polymer, and a second polymer composition layer comprising thrombin and aliphatic polyester.SELECTED DRAWING: None 【課題】止血性蛋白質、つまりフィブリノゲン及び／又はトロンビンの担持性および溶出性が良く、柔軟性（組織追従性）、ひいては止血性に優れたシート成形体の提供。【解決手段】フィブリノゲン又はトロンビンより選ばれる一種以上の蛋白質と、脂肪族ポリエステル及び水溶性ポリマーより選ばれる一種以上のポリマーを含有するポリマー組成物のシート成形体。シート成形体がフィルム成形体または繊維成形体である、又は／及び、フィブリノゲンと水溶性ポリマーを含む第１ポリマー組成物層及びトロンビンと脂肪族ポリエステルを含む第２ポリマー組成物層を含有する積層シート成形体。【選択図】なし