BASE SEQUENCE DETECTION CHIP

• Main Authors: KUWABARA TETSUYA, YUMOTO MASAYUKI, OKADA JUN
• Format: Patent
• Language: English; Japanese
• Published: 25.04.2016
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; SPIRITS; TESTING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide a base sequence detection chip in which sending of air bubbles to a flow channel on an electrode can be suppressed.SOLUTION: A base sequence detection chip of this embodiment comprises: a plurality of electrode groups separately arrayed on a substrate from each other, in which each electrode group has a plurality of separately arranged first electrodes; probes which are provided corresponding to each first electrode, fixed to a corresponding first electrode, and have a base sequence; and a cover member which is provided on the substrate so as to cover the plurality of electrode groups along an array direction of the plurality of electrode groups, forms a flow channel together with the substrate, and has an inlet into which reagent flows and an outlet from which the reagent having passed the flow channel flows out, in which the first electrode closest to the inlet is provided at a position remote from the inlet by 2.0 times or more the width of the flow channel.SELECTED DRAWING: Figure 9 【課題】電極上の流路に気泡が送られることを抑制することのできる塩基配列検出チップを提供する。【解決手段】本実施形態の塩基配列検出チップは、基板上に互いに離間して配列された複数の電極群であって、各電極群は離間して配置された複数の第１電極を有する、複数の電極群と、各第１電極に対応して設けられ、対応する第１電極に固定され、塩基配列を有するプローブと、前記複数の電極群の配列方向に沿って前記複数の電極群を覆うように前記基板上に設けられ、前記基板とともに流路を形成するカバー部材であって、試薬が流入する入口と、前記流路を通過した前記試薬が流出する出口と、を有するカバー部材と、を備え、前記入口に最近接した第１電極は前記入口から前記流路の幅の２．０倍以上離れた位置に設けられている。【選択図】図９