USE OF EFFECTIVE FRACTION OF ALKALOID ORIGINATING FROM MULBERRY BRANCH FOR PREPARING HYPOGLYCEMIC MEDICINE

PROBLEM TO BE SOLVED: To prepare a fraction of an alkaloid having a blood sugar-depressing action from mulberry branches as a raw material.SOLUTION: A fraction as a herbal medicine prepared from mulberry branches includes 50 wt.% of a total alkaloid on the basis of the amount of effective fraction,...

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Main Authors LIU YULING, CHEN ZHEN, WANG RENYUN, LIU QUAN, CHEN YUETENG, SUN SUJUAN, XIA XUEJUN, XIE MINGZHI, SHEN ZHUFANG
Format Patent
LanguageEnglish
Japanese
Published 21.01.2016
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Summary:PROBLEM TO BE SOLVED: To prepare a fraction of an alkaloid having a blood sugar-depressing action from mulberry branches as a raw material.SOLUTION: A fraction as a herbal medicine prepared from mulberry branches includes 50 wt.% of a total alkaloid on the basis of the amount of effective fraction, and not less than 30 wt.% of compound 1-deoxynojirimycin on the basis of the total amount of alkaloid. Also provided are a method of preparing the effective fraction, a pharmaceutical composition containing the effective fraction, and use of the effective fraction for preparing a hypoglycemic medicine. 【課題】血糖降下作用を有する、アルカロイドの有効画分を、桑の枝を原料として調製する。【解決手段】桑の枝から作製される、生薬としての有効画分であって、総アルカロイドが有効画分を基準に50重量%であり、化合物1−ジオキシノジリマイシンが総アルカロイドを基準に30重量%以上である有効画分が、開示される。この有効画分を調製するための方法、およびこの有効画分を含有する薬学的組成物、ならびに血糖降下剤を調製するためのこの有効画分の使用もまた、開示される。【選択図】なし
Bibliography:Application Number: JP20150187139