ORAL CARE METHOD AND KIT

• Main Authors: ALAN R DOMBROWSKI, MATTHEW T SCHOLZ, KATIE F WLASCHIN, RANJANI V PARTHASARATHY
• Format: Patent
• Language: English; Japanese
• Published: 14.01.2016
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide an improved method and product having higher flexibility and efficacy in treating patients according to their individual indications, such as oral sterilization of mechanically ventilated patients, xerostomia, and the like.SOLUTION: The invention relates to a method of moisturizing simultaneously with decolonizing mammalian tissue, the method comprising a step of applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue. The mammalian tissue is oral tissue of a subject, the multi-valent cationic antiseptic is other than a metal ion, the applied compositions essentially exclude any component which causes a precipitate when combined with a multi-valent cationic antiseptic contained in the multi-valent cationic antiseptic composition, and/or the moisturizer composition is such that a log reduction in the number of viable bacterial cells of at least 2 is provided when combined with a mixture of the multi-valent cationic antiseptic composition. The invention also relates to an oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition. 【課題】人工呼吸器装着患者の口腔内殺菌及び口腔乾燥症等の各適応症に応じて患者を治療する際により高い柔軟性及び有効性有する、改善された方法及び製品の提供。【解決手段】多価カチオン性殺菌剤組成物を組織に適用することと、保湿組成物を同じ組織の少なくとも一部に適用することと、を含む、哺乳類の組織を保湿すると同時に脱コロニー化する方法であって、哺乳類の組織が被験体の口腔組織であり；多価カチオン性殺菌剤が、金属イオン以外であり；及び、多価カチオン性殺菌剤組成物に含まれる多価カチオン性殺菌剤と組み合わされると沈殿物を生じさせるあらゆる構成成分を本質的に排除し；並びに／又は保湿組成物が、多価カチオン性殺菌剤組成物との混合物と組み合わされると、生存細菌細胞の数が少なくとも２ｌｏｇ減少するようなものである、方法；多価カチオン性殺菌剤と保湿組成物とを含む組成物を含む口腔ケアキット。【選択図】図１