STABILIZED, ANTIMICROBIAL COMPOSITION WITH A CONTENT OF BISPYRIDINIUM ALKANE

PROBLEM TO BE SOLVED: To provide a stabilized, antimicrobially effective aqueous-based composition including bispyridinium alkane such as octenidine.SOLUTION: A composition of the invention comprises: a) octenidine dihydrochloride; b) at least one stabilizer selected from antioxidants, complexing ag...

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Main Authors DETTMANN ANDREAS, MONA GOLOMBIEWSKI, ELKE KASSENS, BEILFUSS WOLFGANG, THOMAS SPUIDA, BEHRENDS SABINE
Format Patent
LanguageEnglish
Japanese
Published 29.10.2015
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Summary:PROBLEM TO BE SOLVED: To provide a stabilized, antimicrobially effective aqueous-based composition including bispyridinium alkane such as octenidine.SOLUTION: A composition of the invention comprises: a) octenidine dihydrochloride; b) at least one stabilizer selected from antioxidants, complexing agents, reducing agents, UV filters and photoprotecting agents; c) one or more auxiliaries selected from fatty alcohol polyalkoxylates, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, alkylglycosides, and alkoxylated (especially ethoxylated) fatty acid monoglycerides. The presence of the stabilizer reduces or prevents the appearance of decomposition products of octenidine dihydrochloride and of decomposition products of the auxiliaries such as ethers or peroxides in particular, in the presence of the auxiliary agent. 【課題】ビスピリジニウムアルカン(例えばオクテニジン)を含んでなる、安定化された抗菌作用を有する水性ベースの組成物の提供。【解決手段】a)オクテニジンジヒドロクロリドと、b)酸化防止剤、錯化剤、還元剤、UVフィルター及び光防護剤から選択される少なくとも1の安定剤と、c)脂肪族アルコールポリアルコキシレート,ソルビタン脂肪酸エステル,ポリオキシエチレンソルビタン脂肪族エステル,アルキルグリコシド,及びアルコキシル化(特にエトキシル化)脂肪酸モノグリセリドから選択される1以上の補助剤とを含む組成物。【効果】前記安定剤の存在は、補助剤が存在する場合において、オクテニジンジヒドロクロリドの分解産物、並びにエーテル及び過酸化物のような補助剤の分解産物の出現を低減する、又は妨げる効果を有する。【選択図】なし
Bibliography:Application Number: JP20150090570