CELL ANALYZER AND CELL ANALYSIS METHOD

PROBLEM TO BE SOLVED: To discriminate a cancer cell with higher accuracy.SOLUTION: A first histogram acquisition part 11 acquires a first histogram of fluorescence intensity by using a measurement result of the number of cells which are subjected to cell nucleus dyeing. A second histogram acquisitio...

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Bibliographic Details
Main Authors SHIOYAMA TAKAHIRO, KATO HIROSHI, TAKEDA SUNAO, SUZUKI AKANE, HINATA NAE, KUBO HIROTSUGU, NOMURA KENICHI
Format Patent
LanguageEnglish
Japanese
Published 30.03.2015
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:PROBLEM TO BE SOLVED: To discriminate a cancer cell with higher accuracy.SOLUTION: A first histogram acquisition part 11 acquires a first histogram of fluorescence intensity by using a measurement result of the number of cells which are subjected to cell nucleus dyeing. A second histogram acquisition part 12 acquires a second histogram which is normalized based on an intensity value of fluorescence indicating the maximum value of the first histogram. A determination part 14 determines presence/absence of cancer cells based on any one of the first histogram and the second histogram. An output part 15 outputs a determination result by the determination part 14. 【課題】がん細胞の識別をより高い精度で行なえるようにする。【解決手段】第１ヒストグラム取得部１１は、細胞核染色された細胞数の計測結果を用いて蛍光強度の第１ヒストグラムを取得する。第２ヒストグラム取得部１２は、第１ヒストグラムの最大値を示す蛍光強度値に基づいて規格化された第２ヒストグラムを取得する。判定部１４は、第１ヒストグラムと第２ヒストグラムのいずれかに基づいて、がん細胞の有無を判定する。出力部１５は、判定部１４による判定結果を出力する。【選択図】図１
Bibliography:Application Number: JP20130193949