EXTENDED TREATMENT OF MULTIPLE SCLEROSIS
PROBLEM TO BE SOLVED: To provide a method for treating a subject having multiple sclerosis comprising a step of administering to the subject a therapeutically effective amount of VLA-4 binding antibody for at least 24 hours.SOLUTION: Provided is a method for treating a subject having multiple sclero...
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Main Authors | , , |
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Format | Patent |
Language | English Japanese |
Published |
19.03.2015
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Subjects | |
Online Access | Get full text |
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Summary: | PROBLEM TO BE SOLVED: To provide a method for treating a subject having multiple sclerosis comprising a step of administering to the subject a therapeutically effective amount of VLA-4 binding antibody for at least 24 hours.SOLUTION: Provided is a method for treating a subject having multiple sclerosis comprising a step of administering to the subject a therapeutically effective amount of a VLA-4 binding antibody for at least 24 hours. Particularly, the method for treating a subject having multiple sclerosis comprises a step of selecting a subject on the basis of having previously had at least 22 doses of VLA-4 binding antibody for 24 months; and administering to the subject an additional course of VLA-4 binding antibody treatment to provide an improved therapeutic result relative to before the commencement of VLA-4 binding antibody treatment.
【課題】多発性硬化症(MS)を有する被験体を処置する方法であって、当該方法は、当該被験体に対して、治療上有効な量のVLA−4結合抗体を少なくとも24時間投与する工程;を包含する、方法の提供。【解決手段】多発性硬化症(MS)を有する被験体を処置する方法であって、当該方法は、当該被験体に対して、治療上有効な量のVLA−4結合抗体を少なくとも24時間投与する工程;を包含する、方法。多発性硬化症(MS)を有する被験体を処置する方法であって、当該方法は、24ヶ月間にわたって少なくとも22回分の用量のVLA−4結合抗体を受けた患者を選択する工程;および当該患者に対して、VLA−4結合抗体治療の開始前と比較して改善された治療効果を提供するために十分なVLA−4結合抗体治療を少なくとも1クール投与する工程;を包含する、方法。【選択図】なし |
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Bibliography: | Application Number: JP20140252699 |