BIOCOMPATIBLE POLYACRYLATE COMPOSITIONS FOR MEDICAL APPLICATIONS

• Main Author: HOSSAINY SYED F A
• Format: Patent
• Language: English; Japanese
• Published: 05.03.2015
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROSTHESES; TREATMENT OR PROTECTION OF EYES OR EARS

PROBLEM TO BE SOLVED: To provide stent coatings having the advantage that although coated stents improve pharmacological treatment of a patient and improve biocompatibility of a medical device in the patient, coatings can still be improved, and in particular, it is desirable to have biologically beneficial (biobeneficial) stent coatings that are creep compliant and are capable of providing modulated drug release rate by increased water absorption in the overall coating.SOLUTION: A composition is disclosed which comprises: a structural component comprising linear acrylic homopolymers or linear acrylic copolymers; and a biobeneficial component comprising copolymers having an acrylate moiety and a biobeneficial moiety. 【課題】コーティングされたステントは患者の薬物治療を改善し、患者における医療デバイスの生体適合性を改善するが、コーティングは更に改善することが可能である。特に、クリープコンプライアントであって、コーティング全体の吸水率の増加により調節された薬剤放出速度を提供することが可能な生物学的に有益な（生体有益性）ステント用コーティングを有することが望ましい。本発明の実施形態はこれらの利点及び他の利点を有するステント用コーティングを提供する。【解決手段】直鎖アクリルホモポリマー又は直鎖アクリルコポリマーを含む構造要素と、アクリレート成分及び生体有益性成分を有するコポリマーを含む生体有益性要素を含む組成物を開示する。【選択図】なし