ADVANCED GLYCATION END PRODUCTS FORMATION INHIBITOR

• Main Authors: KAWAURA RYOSUKE, OTSUKA RYOICHI, KATSUBE TOMOKO, SHONO YUKO, KITABAYASHI KENICHI, MOTOMURA YOSUKE
• Format: Patent
• Language: English; Japanese
• Published: 05.02.2015
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

PROBLEM TO BE SOLVED: To provide an advanced glycation end products formation inhibitor with a few side effects, to provide a pharmaceutical composition useful for prevention and/or treatment of diabetes or diabetic complications with a few side effects, and to provide an external preparation for skin useful for prevention and/or improvement of skin aging with a few side effects.SOLUTION: The invention provides an advanced glycation end products formation inhibitor containing one or more kinds of anti-glycation plant extracts selected from the group consisting of Lemon Myrtle extract, Glehnia littoralis extract, and Manihot utilissima extract. A pharmaceutical composition and an external preparation for skin containing such anti-glycation plant extracts as active ingredients are also provided. 【課題】副作用の少ない終末糖化産物生成抑制剤を提供すること。また、糖尿病もしくは糖尿病合併症の予防および／または治療に有用であり、且つ副作用の少ない医薬組成物、ならびに皮膚老化の予防および／または改善に有用であり、且つ副作用の少ない皮膚外用剤を提供すること。【解決手段】レモンマートル抽出物、ハマボウフウ抽出物およびキャッサバ抽出物からなる群より選ばれる１種以上の抗糖化植物抽出物を有効成分として含有する終末糖化産物生成抑制剤を提供する。また、かかる抗糖化植物抽出物を有効成分として含有する医薬組成物および皮膚外用剤を提供する。【選択図】なし