TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS THE SAME AND EXHIBITS ANALGESIC ACTIVITY

PROBLEM TO BE SOLVED: To provide methods of producing compounds having novel P2Xand/or P2Xreceptor antagonistic effect.SOLUTION: The producing method is characterized by reaction of a compound represented by formula (X), where Zand Zare an oxygen atom or the like; Ris alkyl or the like; Ris alkyl or...

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Main Authors KAMEYAMA TAKAYUKI, FUJII YASUHIKO, TADA YUKIO, KAI HIROYUKI, HASEGAWA TAKESHI, NAOHARA AYAE, HORIGUCHI TORU, NAKAMURA KENICHIRO, ASAHI KENTARO, MAKI TOSHIKATSU, ENDO TAKESHI, OHARA MIHO, SHINTANI TAKUYA, IIDA SEI
Format Patent
LanguageEnglish
Japanese
Published 23.10.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:PROBLEM TO BE SOLVED: To provide methods of producing compounds having novel P2Xand/or P2Xreceptor antagonistic effect.SOLUTION: The producing method is characterized by reaction of a compound represented by formula (X), where Zand Zare an oxygen atom or the like; Ris alkyl or the like; Ris alkyl or the like; Ris alkyl; and n' is 0-3, or salt thereof. 【課題】新規なＰ２Ｘ3および／またはＰ２Ｘ2/3受容体拮抗作用を有する化合物の製造方法を提供する。【解決手段】式（Ｘ）：【化１】［式中、Ｚ１およびＺ２は酸素原子等；Ｒｆ１はアルキル等；Ｒｃ１はアルキル等；Ｒ２７はアルキル; ｎ'は０〜３］で示される化合物またはその塩を反応させることを特徴とする、製造方法。【選択図】なし
Bibliography:Application Number: JP20140153414