MANUFACTURING METHOD OF OPTICALLY ACTIVE BENZAMIDE DERIVATIVE

PROBLEM TO BE SOLVED: To provide a novel manufacturing method of an optically active N-morpholinyl methyl benzamide derivative (1) exhibiting a strong affinity to a serotonine 4 receptor and effective as a drug for enterokinesis enhancement or digestive tract function improvement.SOLUTION: A manufac...

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Bibliographic Details
Main Authors KURODA KIICHI, WATANABE SHOJI, TSUKIMURA TAKASHI
Format Patent
LanguageEnglish
Published 07.07.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:PROBLEM TO BE SOLVED: To provide a novel manufacturing method of an optically active N-morpholinyl methyl benzamide derivative (1) exhibiting a strong affinity to a serotonine 4 receptor and effective as a drug for enterokinesis enhancement or digestive tract function improvement.SOLUTION: A manufacturing method of an optically active N-morpholinyl methyl benzamide derivative (1) uses a novel optically active N-morpholinyl methyl benzamide intermediate product. (In the formula, Rdenotes a hydrogen atom or a halogen atom, Rdenotes a hydrogen atom or an alkyl group, Rdenotes a hydrogen atom, an alkyl group or an alkanoyl, and Rdenotes a hydrogen atom, an alkyl group, an alkenyl group or an alkynyl group.)
Bibliography:Application Number: JP20120284246