NOVEL CARBOXYLIC ACID DERIVATIVES AND PRODRUGS

PROBLEM TO BE SOLVED: To provide compounds which have antagonistic actions against prostaglandin E(PGE) receptor subtype EP3 and are effective in preventing and/or treating various diseases associated with EP3 receptor operation.SOLUTION: Provided are compounds represented by the specified general f...

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Main Authors KURITA NAOKI, WATANABE YOSUKE, NAGATA OSAMU, KATO HIROSHIGE, AMADA JUNICHIRO, MIYATA SAHO, YOSHINO YASUHIRO, OOKA YUKO, KAWASAKI NOBUHIDE, IWABUCHI TAKEYUKI
Format Patent
LanguageEnglish
Published 17.04.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide compounds which have antagonistic actions against prostaglandin E(PGE) receptor subtype EP3 and are effective in preventing and/or treating various diseases associated with EP3 receptor operation.SOLUTION: Provided are compounds represented by the specified general formula (1), where R, R, R, R, Rand A are defined in the specifications, pharmaceutically acceptable salts thereof, and hydrates and solvates of them.
Bibliography:Application Number: JP20120226403