ITRACONAZOLE COMPOSITION WITH IMPROVED BIOAVAILABILITY

PROBLEM TO BE SOLVED: To provide dosage forms of itraconazole with excellent bioavailability.SOLUTION: A solid dispersion product comprises itraconazole and hydroxypropyl methylcellulose, which satisfies the formula 0.35> H(1) (where Hrepresents the endothermic amount (J/g) accompanying a transit...

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Bibliographic Details
Main Authors GARRIT DISPERSYN, MARKUS MAGERLEIN, GUNTHER BERNDL, MATTHIAS DEGENHARDT
Format Patent
LanguageEnglish
Published 10.04.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide dosage forms of itraconazole with excellent bioavailability.SOLUTION: A solid dispersion product comprises itraconazole and hydroxypropyl methylcellulose, which satisfies the formula 0.35> H(1) (where Hrepresents the endothermic amount (J/g) accompanying a transition at about 240°C).
Bibliography:Application Number: JP20130248144