MASS SPECTROMETRY OF SUGAR PEPTIDE

PROBLEM TO BE SOLVED: To provide a method to generate the cleavage required for analysis in mass spectrometry of sugar peptides having arginine residues.SOLUTION: A mass spectrometry of sugar peptides includes: a step in which a sugar peptide having a guanidino group is subjected to alteration of th...

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Bibliographic Details
Main Authors TANIGUCHI KENICHI, TANAKA KOICHI, KUYAMA HIROKI
Format Patent
LanguageEnglish
Published 31.10.2013
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:PROBLEM TO BE SOLVED: To provide a method to generate the cleavage required for analysis in mass spectrometry of sugar peptides having arginine residues.SOLUTION: A mass spectrometry of sugar peptides includes: a step in which a sugar peptide having a guanidino group is subjected to alteration of the guanidino group or removal of the guanidino group, and a sugar peptide that does not include the guanidino group is obtained; and a step in which the sugar peptide that does not include the guanidino group is subjected to mass spectrometry, and a sugar chain cleavage-derived fragment ion and a peptide chain cleavage-derived fragment ion are obtained.
Bibliography:Application Number: JP20120097187