CHEMOKINE RECEPTOR ANTAGONIST AND METHOD OF USE THEREOF

PROBLEM TO BE SOLVED: To provide a low-molecular compound which is a modulator of a chemokine receptor function.SOLUTION: There are provided a compound represented by the formula, which is an antagonist of a chemokine receptor function, and a physiologically acceptable salt thereof. In the formula,...

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Main Authors LULY JAY R, NAKASATO YOSHISUKE, OSHIMA ETSUO, MATTIA KAREN M, GHOSH SHOMIR, ELDER AMY M, HARRIMAN GERALDINE C B, CARSON KENNETH G
Format Patent
LanguageEnglish
Published 10.10.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a low-molecular compound which is a modulator of a chemokine receptor function.SOLUTION: There are provided a compound represented by the formula, which is an antagonist of a chemokine receptor function, and a physiologically acceptable salt thereof. In the formula, n is 1 to 4; M is a methylene group containing a halophenyl group or the like; Rand Rare independently a hydrogen atom or a methyl group; Rand Rare independently a methyl group or the like; and Z is a nitrogen-containing heterocyclic residue or the like.
Bibliography:Application Number: JP20130101580