RELEASE-CONTROL COMPOSITION

PROBLEM TO BE SOLVED: To provide a release control composition which release a pharmaceutically active agent for a long period of time and exhibits not only proper drug release properties but also melt processing characteristics suitable to drug support and has elasticity at body temperature.SOLUTIO...

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Bibliographic Details
Main Authors ZURUTUZA AMAIA, TUOMINEN JUKKA, LIVINGSTON MARK, HALLIDAY JANET A
Format Patent
LanguageEnglish
Published 08.08.2013
Subjects
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS
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Summary:PROBLEM TO BE SOLVED: To provide a release control composition which release a pharmaceutically active agent for a long period of time and exhibits not only proper drug release properties but also melt processing characteristics suitable to drug support and has elasticity at body temperature.SOLUTION: A pharmaceutical release control composition comprises a water swellable linear polymer obtained by a reaction of polyethylene glycol, polypropylene glycol, a diol and a diisocyanate, and a pharmaceutically active agent. A release control composition includes the water swellable linear polymer obtained by a reaction of polyethylene glycol, polypropylene glycol, a diol and a diisocyanate, wherein the molar ratio of the components (i):(ii):(iii):(iv) is 1:1:1:3.
Bibliography:Application Number: JP20130043282