QUINOLINONE DERIVATIVES AS TYROSINE KINASE INHIBITORS

PROBLEM TO BE SOLVED: To provide variety of chemicals to provide VEGF-RTK antagonist therapies.SOLUTION: Organic compounds having the formulas I and II are provided where the variables have the values described herein. Pharmaceutical formulations include the organic compounds or pharmaceutically acc...

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Bibliographic Details
Main Authors TAYLOR CLARKE, MCCREA BILL, MACHAJEWSKI TIM, RENHOWE PAUL, MCBRIDE CHRIS, JAZAN ELISA, PECCHI SABINA, SHAFER CYNTHIA
Format Patent
LanguageEnglish
Published 23.05.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide variety of chemicals to provide VEGF-RTK antagonist therapies.SOLUTION: Organic compounds having the formulas I and II are provided where the variables have the values described herein. Pharmaceutical formulations include the organic compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and may be prepared by mixing the organic compounds or pharmaceutically acceptable salts of the organic compounds with a carrier and water. A method of treating a patient includes administering a pharmaceutical formulation to a patient in need thereof.
Bibliography:Application Number: JP20130013940