BENZIMIDAZOLONE AND OXINDOLE DERIVATIVE, AND PHARMACEUTICAL APPLICATION OF THEM

PROBLEM TO BE SOLVED: To provide a therapeutic agent or a prophylactic agent of various kinds of diseases or symptoms (particularly neuropsychiatric disease such as Alzheimer's dementia) involving a serotonin 4 receptor.SOLUTION: There is provided a compound represented by formula (1) or a phar...

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Main Authors IKEDA JUNYA, NAKAMURA TAKANORI, OTAKA HIROMICHI, MIZUNO KAZUHIRO, GOTO NANA
Format Patent
LanguageEnglish
Published 17.01.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a therapeutic agent or a prophylactic agent of various kinds of diseases or symptoms (particularly neuropsychiatric disease such as Alzheimer's dementia) involving a serotonin 4 receptor.SOLUTION: There is provided a compound represented by formula (1) or a pharmaceutically acceptable salt thereof [in the formula, A represents formula (A-1) or else, B represents formula (B-2) or else, D represents (R-1) or else, U represents carbon atom or nitrogen atom, X, Y and Z represent oxygen atom, nitrogen atom, sulfur atom or carbon atom, V represents oxygen atom or sulfur atom, W represents N-Ror CRR, R, R, Rand Rrepresent hydrogen atom, halogen atom, alkyl group or else, R, R, Rand Rrepresent hydrogen atom, halogen atom, hydroxy group, alkyl group or else, Rrepresents hydrogen atom, alkyl group, -CORand -COORor else, l represents an integer of 0 to 4, r, r', s and s' represent integers of 0 to 3].
Bibliography:Application Number: JP20110145078