CELL CULTURE MEMBRANE, CELL CULTURE SUBSTRATE, AND METHOD FOR MANUFACTURING CELL CULTURE SUBSTRATE

PROBLEM TO BE SOLVED: To provide a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and chemical resistance, has excellent cell adhesion properties and long-term culture propert...

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Main Authors HIRAMA MAKOTO, KIMURA KEISHI, INOUE TAKASHI, OGUNI TAKU, MOCHIZUKI TSUTOMU, TOZAWA HIDETO, YOSHIMOTO YASUO, UEMAE KENTARO, FUJII TERUO, TANABE YUKI
Format Patent
LanguageEnglish
Published 10.01.2013
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Summary:PROBLEM TO BE SOLVED: To provide a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and chemical resistance, has excellent cell adhesion properties and long-term culture properties, and is capable of replicating a cell adhesion morphology that is similar to that of collagen derived from living organisms and being used for conventional cell cultivation; and also to provide a cell culture substrate, and a method for manufacturing the cell culture substrate.SOLUTION: A polymer membrane represented by formula (I) is formed on the base of a cell culture substrate so as to have a membrane thickness equal to or greater than 0.2 μm (In the formula, R1 and R2 represent a -(CH)-NHmoiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a -(CH2)n-NH2 moiety. l and m are positive integers expressing polymerization degree).
Bibliography:Application Number: JP20110140961