LOW DOSE ENTECAVIR FORMULATION AND USE OF THE SAME

PROBLEM TO BE SOLVED: To provide a low dose Entecavir-containing formulation capable of once daily administration for treatment of hepatitis B virus infectious disease and/or a simultaneous infection, and a method for manufacturing the same.SOLUTION: Disclosed is a pharmaceutical composition in tabl...

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Bibliographic Details
Main Authors COLONNO RICHARD J, SPROCKEL OMAR L, FAKES MICHAEL G, HARIANAWALA ABIZER, DESAI DIVYAKANT
Format Patent
LanguageEnglish
Published 27.12.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a low dose Entecavir-containing formulation capable of once daily administration for treatment of hepatitis B virus infectious disease and/or a simultaneous infection, and a method for manufacturing the same.SOLUTION: Disclosed is a pharmaceutical composition in tablet or capsule form containing 0.5 mg/form of Entecavir attached by povidone as an adhesive to a pharmaceutically acceptable carrier. It is all right even if any other pharmaceutically active substance is contained in the Entecavir composition, or if such a substance is dosed separately from the Entecavir composition.
Bibliography:Application Number: JP20120183484