PROCESS FOR PRODUCE OF BENZOIC ACID

PROBLEM TO BE SOLVED: To provide a process for the produce of aromatic carboxylic acids or aromatic acid chlorides having substituents such as an alkoxy, a hydroxy, a formyloxy or an alkanoyloxy on the aromatic ring.SOLUTION: The process for the produce of the compound of formula (IV) includes the s...

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Bibliographic Details
Main Authors JOSHI SUDHIR RAMTIRTH, WU CHARLES CHAO, CHONG JOSHUA ANTHONY, ABDESAKEN FEREYDON, SPANGLER LORI ANN
Format Patent
LanguageEnglish
Published 27.12.2012
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:PROBLEM TO BE SOLVED: To provide a process for the produce of aromatic carboxylic acids or aromatic acid chlorides having substituents such as an alkoxy, a hydroxy, a formyloxy or an alkanoyloxy on the aromatic ring.SOLUTION: The process for the produce of the compound of formula (IV) includes the steps of (i) reacting a compound having a halogen with magnesium metal under anhydrous conditions to form an intermediate compound, (ii) reacting the obtained intermediate compound with carbon dioxide to form a compound of formula (VIb) after hydrolysis, and (iii) reacting the compound of formula (VIb) with sodium hydroxide, or the like, to form a compound of formula (IV), wherein each X is independently chloro, bromo or iodo and R is a hydrogen atom, (C-C)alkyl, or the like, Ris aryl, aryl(C-C)alkyl, or the like.
Bibliography:Application Number: JP20120179852