METHOD FOR PRODUCING CANDESARTAN CILEXETIL-CONTAINING GRANULE AND METHOD FOR PRODUCING CANDESARTAN CILEXETIL-CONTAINING TABLET

PROBLEM TO BE SOLVED: To provide a method for producing candesartan cilexetil-containing granules wherein candesartan cilexetil is prevented from decomposing and stabilized, and a method for producing a candesartan cilexetil-containing tablet wherein candesartan cilexetil is prevented from decomposi...

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Bibliographic Details
Main Authors UETSUKI KENJI, FUKUHARA YASUSHI, NAKAGAWA TOMOYA, HIZAKI MASAYA
Format Patent
LanguageEnglish
Published 30.08.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a method for producing candesartan cilexetil-containing granules wherein candesartan cilexetil is prevented from decomposing and stabilized, and a method for producing a candesartan cilexetil-containing tablet wherein candesartan cilexetil is prevented from decomposing and stabilized.SOLUTION: In the method for producing candesartan cilexetil-containing granules, a mixture containing candesartan cilexetil and D-mannitol is granulated in a fluidized bed. Granules obtained by this method, the method for producing a candesartan cilexetil-containing tablet by forming the granules into a tablet, and the candesartan cilexetil-containing tablet obtained by the method are also provided.
Bibliography:Application Number: JP20110022277