METHOD FOR PRODUCING trans-4-AMINO ADAMANTANE-1-CARBOXAMIDE

PROBLEM TO BE SOLVED: To provide a new method for producing trans-4-amino adamantane-1-carboxamide or an acid addition salt thereof, which is useful as an intermediate of an active pharmaceutical ingredient of a therapeutic agent of diabetes etc.SOLUTION: The method for producing the trans-4-amino a...

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Bibliographic Details
Main Authors UNO SHINSAKU, KONDO TOMOAKI, SENAMI KENTO, HORIUCHI YOSHIHIRO
Format Patent
LanguageEnglish
Published 02.08.2012
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:PROBLEM TO BE SOLVED: To provide a new method for producing trans-4-amino adamantane-1-carboxamide or an acid addition salt thereof, which is useful as an intermediate of an active pharmaceutical ingredient of a therapeutic agent of diabetes etc.SOLUTION: The method for producing the trans-4-amino adamantane-1-carboxamide includes bringing a mixture containing an amine, such as benzylamine, and 4-oxoadamantane-1-carboxamide with hydrogen in the presence of a hydrogenation catalyst.
Bibliography:Application Number: JP20110278038