PREVENTIVE AND/OR THERAPEUTIC AGENT FOR OSTEOPOROSIS, BONE RESORPTION INHIBITOR, OSTEOGENESIS PROMOTER AND SCREENING METHOD FOR THESE

• Main Authors: HII EIICHI, TAKARADA TSUYOSHI, FUJITA HIROYUKI, YONEDA YUKIO
• Format: Patent
• Language: English
• Published: 17.05.2012
• Subjects: HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TESTING

PROBLEM TO BE SOLVED: To provide a pharmaceutical useful for preventing and/or treating osteoporosis that inhibits osteoclast differentiation and promotes osteoblast differentiation, and a screening method for the same.SOLUTION: The preventive and/or therapeutic agent for osteoporosis comprises an L-amino acid transporter inhibitor. The screening method for a candidate substance for preventive and/or therapeutic agent for osteoporosis comprises a step of evaluating whether a subject substance can inhibit an L-amino acid transporter or not.