IMMUNOSTIMULATORY INOSINE MONOPHOSPHATE 5'-NUCLEOTIDASE RESISTANT DERIVATIVE, AND ITS USE

PROBLEM TO BE SOLVED: To provide an inosine-5'-monophosphate derivative which has higher immunostimulatory capacity, is more stable and has resistance to 5'-nucleotidase.SOLUTION: Regarding the method for producing inosine-5'-monophosphate or its derivative having resistance to 5'...

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Bibliographic Details
Main Authors HADDEN JOHN W, GINER SOROLLA ALFREDO, MASIHI NOEL K
Format Patent
LanguageEnglish
Published 05.01.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide an inosine-5'-monophosphate derivative which has higher immunostimulatory capacity, is more stable and has resistance to 5'-nucleotidase.SOLUTION: Regarding the method for producing inosine-5'-monophosphate or its derivative having resistance to 5'-nucleotidase, the method chemically denaturalizes inosine-5'-monophosphate to a compound expressed by formula (I) and holds the biological activity of the inosine-5'-monophosphate in the living body (In the formula, R is selected from a group composed of alkyl, alkoxy and the second amino compound.).
Bibliography:Application Number: JP20110177779