HYBRID POLYPEPTIDE WITH SELECTABLE PROPERTIES

PROBLEM TO BE SOLVED: To provide agents for the treatment and prevention of metabolic diseases and disorders which can be alleviated by controlling glucose levels, insulin levels, and/or insulin secretion, such as diabetes and diabetes-related conditions.SOLUTION: Hybrid polypeptides comprise a firs...

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Main Authors SOARES CHRISTOPHER J, LEWIS DIANA Y, GHOSH SOUMITRA S, JODKA CAROLYN M, D'SOUZA LAWRENCE J, PARKES DAVID G, ODILE ESTHER LEVY, HANLEY MICHAEL R, MACK CHRISTINE M
Format Patent
LanguageEnglish
Published 04.11.2011
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide agents for the treatment and prevention of metabolic diseases and disorders which can be alleviated by controlling glucose levels, insulin levels, and/or insulin secretion, such as diabetes and diabetes-related conditions.SOLUTION: Hybrid polypeptides comprise a first bio-active peptide hormone module covalently linked to at least one more bio-active peptide hormone module, wherein the bio-active peptide hormone module is selected from a component peptide hormone, etc., which is selected from amylin, etc., and at least one of the bio-active peptide hormone modules exhibits at least one hormonal activity of the component peptide hormone.
Bibliography:Application Number: JP20110137394