METHOD FOR DETECTING ESOPHAGUS CANCER OR PREDICTING PROGNOSIS OF ESOPHAGUS CANCER, AND ESOPHAGUS CANCER INHIBITOR

• Main Authors: INASAWA JOJI, IMOTO TOSHINARI, HARUKI SHIGEO
• Format: Patent
• Language: English
• Published: 15.09.2011
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide a method for detecting esophagus cancer or predicting the prognosis of the esophagus cancer by newly discovering a cancer-inhibiting gene associated with the esophagus cancer, and analyzing the change of the inhibiting gene, to provide an esophagus cancer inhibitor containing the cancer-inhibiting gene, and to provide the esophagus cancer inhibitor containing a protein encoded by the cancer-inhibiting gene. SOLUTION: The method for detecting the esophagus cancer or predicting the prognosis of the esophagus cancer includes a step for analyzing the change of PCDH17 gene in a specimen. The esophagus cancer inhibitor contains the PCDH17 gene or a homologous gene thereof. In another embodiment, the esophagus cancer inhibitor contains PCDH17 protein or a homologous protein thereof. COPYRIGHT: (C)2011,JPO&INPIT