FLUOROUS SIALIC ACID DERIVATIVE AND ANALYSIS METHOD THEREFOR

PROBLEM TO BE SOLVED: To provide a detection method of a fluorous sialic acid derivative which is detected by an LC-MS/MS method. SOLUTION: A fluorous sialic acid derivative can be detected by an LC-MS/MS method, and is represented by general formula [I] äin the formula, R1is a glycolyl group, or th...

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Main Authors YAMAGUCHI MASATOSHI, NODA HITOSHI, ITOYAMA MIKI, SAKAGUCHI YOHEI, YOSHIDA HIDEYUKI, HAYAMA TADASHI, TODOROKI KENICHIRO
Format Patent
LanguageEnglish
Published 02.06.2011
Subjects
CHEMISTRY
DERIVATIVES THEREOF
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PHYSICS
SUGARS
TESTING
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Summary:PROBLEM TO BE SOLVED: To provide a detection method of a fluorous sialic acid derivative which is detected by an LC-MS/MS method. SOLUTION: A fluorous sialic acid derivative can be detected by an LC-MS/MS method, and is represented by general formula [I] äin the formula, R1is a glycolyl group, or the like, R2, R3, R4are each hydrogen atom or the like, Ph is a phenylene group, a is an integer of 1-3, b is an integer of 0 or 1, c is an integer of 1-3, and Rf is a fluoroalkyl group represented by general formula [II] (in the formula, R9, R10are each an hydrogen atom or a fluorine atom, and d is an integer of 4-10.)}. COPYRIGHT: (C)2011,JPO&INPIT
Bibliography:Application Number: JP20090264030