DEVICE AND METHOD FOR PATHOGEN INACTIVATION OF THERAPEUTIC FLUID WITH STERILIZING RADIATION

• Main Authors: STERNBERG SHMUEL, SANDFORD CRAIG, KHARE ATUL, BOGGS DANIEL R, WOO LECON, BREILLATT JULIAN
• Format: Patent
• Language: English
• Published: 19.05.2011
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL

PROBLEM TO BE SOLVED: To provide a continuous flow device and method that are highly effective in uniformly irradiating high optical density fluids having low radiation penetrations. SOLUTION: There are provided the device and method for inactivating pathogens in therapeutic fluids with sterilizing radiation in a continuous flow arrangement while exhibiting radiation dose uniformity and narrow residence time distribution of the fluid within the device. The device 10 comprises a radiation permeable cylindrical tube 12 having a concentric cylindrical rotor disposed therein, thereby providing a thin gap 16 therebetween. A top plate 18 having a fluid outlet 26 and a bottom plate 20 having a fluid inlet 24 seal the cylindrical tube 12. The inlet 24 and outlet 26 are both in fluid communication with the thin gap. A rotor shaft 36 is disposed axially through the cylindrical rotor 14 and is connected to a motor 30. COPYRIGHT: (C)2011,JPO&INPIT