EXTERNAL PREPARATION FOR SKIN
PROBLEM TO BE SOLVED: To provide an external preparation for skin which does not separate a tranexamic acid crystal in an external preparation compounding tranexamic acid. SOLUTION: A long-chain acylsulfonate anionic surfactant of 0.01-5 mass% represented by general formula (1): R1CO-a-(CH2)nSO3M1su...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
28.04.2011
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Subjects | |
Online Access | Get full text |
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Summary: | PROBLEM TO BE SOLVED: To provide an external preparation for skin which does not separate a tranexamic acid crystal in an external preparation compounding tranexamic acid. SOLUTION: A long-chain acylsulfonate anionic surfactant of 0.01-5 mass% represented by general formula (1): R1CO-a-(CH2)nSO3M1such as (A) a higher alcohol and (B) a stearoyl methyl taurate, and (C) tranexamic acid of 0.1-5 mass% are compounded and a pH is adjusted to be 3.0-6.0. [In the formula, R1CO- is a saturated or unsaturated fatty acid residue having an average of 10-22 carbon atoms; a is -O- or -NR2- (R2is a hydrogen atom or an alkyl group having 1-3 carbon atoms); M1is a hydrogen atom, alkali metals, alkaline earth metals, ammonium or organic amines; n is an integer from 1 to 3]. COPYRIGHT: (C)2011,JPO&INPIT |
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Bibliography: | Application Number: JP20100159364 |