METHOD FOR ASSESSMENT OF ONSET RISK OF UROTHELIAL CARCINOMA USING BAC CLONE, AND METHOD FOR PREDICTING PROGNOSIS OF THE RISK

PROBLEM TO BE SOLVED: To provide new methods for determining the risk of onset of urothelial carcinoma and prognostic defect risk, or recurrence risk in bladder of renal pelvis-ureteral cancer. SOLUTION: The methods includes the steps of: (a) preparing urothelial-derived genomic DNA of a relevant su...

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Bibliographic Details
Main Authors ARAI SHIGESATO, INASAWA JOJI, KANAI YAE, NISHIYAMA NAOTAKA
Format Patent
LanguageEnglish
Published 24.09.2010
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:PROBLEM TO BE SOLVED: To provide new methods for determining the risk of onset of urothelial carcinoma and prognostic defect risk, or recurrence risk in bladder of renal pelvis-ureteral cancer. SOLUTION: The methods includes the steps of: (a) preparing urothelial-derived genomic DNA of a relevant subject; (b) examining the presence/absence of a DNA methylation in an urothelial carcinoma onset-associated region, urothelial carcinoma prognosis-associated, or renal pelvis-ureteral cancer prognosis prognosis-associated region, as for the genomic DNA prepared in the step (a); and (c) determining whether the subject is classified as a carcinogenesis high-risk group, prognosis defect group, or in-bladder recurrence high-risk group, based on a DNA methylation pattern clarified in the step (b). COPYRIGHT: (C)2010,JPO&INPIT
Bibliography:Application Number: JP20090058156