AZITHROMYCIN DOSAGE FORM WITH REDUCED SIDE EFFECT

PROBLEM TO BE SOLVED: To provide an azithromycin dosage form which has bioavailability analogical to an instantly dischargeable azithromycin with the same dose and has gastrointestinal side effect smaller than the bioavailability. SOLUTION: The azithromycin dosage form includes azithromycin multipar...

Full description

Saved in:
Bibliographic Details
Main Authors MCCRAY SCOTT B, THOMBRE AVINASH GOVIND, CREW MARSHALL D, LO JULIAN BELKNAP, APPEL LEAH E, LYON DAVID K, WEST JAMES B, HERBIG SCOTT MAX, DWAYNE THOMAS FREESEN, HAGEN TIMOTHY A
Format Patent
LanguageEnglish
Published 17.06.2010
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
Online AccessGet full text

Cover

More Information
Summary:PROBLEM TO BE SOLVED: To provide an azithromycin dosage form which has bioavailability analogical to an instantly dischargeable azithromycin with the same dose and has gastrointestinal side effect smaller than the bioavailability. SOLUTION: The azithromycin dosage form includes azithromycin multiparticles and an effective amount of an alkalizing agent. Preferably, the alkalizing agent includes an aluminum salt, a magnesium salt, a calcium salt, a bicarbonate, a phosphate, a metal hydroxide, a metal oxide, N-methylglucamine, arginine, an arginine salt, an amine, or a combination thereof. COPYRIGHT: (C)2010,JPO&INPIT
Bibliography:Application Number: JP20100044743