COMPOSITION CONTAINING DIPHOSPHONIC ACID

PROBLEM TO BE SOLVED: To provide a pharmaceutical administration pattern which is applicable for both high-content and low-content administration patterns of an active component, which is a diphosphonic acid or physiologically appropriate salts of the same, and the active substance is uniformly and...

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Bibliographic Details
Main Authors GABEL ROLF-DIETER, WOOG HEINRICH, PREIS WALTER
Format Patent
LanguageEnglish
Published 27.05.2010
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a pharmaceutical administration pattern which is applicable for both high-content and low-content administration patterns of an active component, which is a diphosphonic acid or physiologically appropriate salts of the same, and the active substance is uniformly and almost completely discharged in 30 minutes and sufficiently stable such that its solubilily does not decrease even after a temperature stress. SOLUTION: This solid pharmaceutical administration pattern includes diphosphonic acid or physiologically appropriate salts of the same such as ibandronate, etidronate, clodronate, risedronate, pamidronate or alendronate, as the active substance, wherein the active substance (in certain instances contains also a pharmaceutical adjuvant drug) exists in a granule form in the inner phase, and the outer phase contains less than 5 wt.% lubricant in a form of stearic acid. COPYRIGHT: (C)2010,JPO&INPIT
Bibliography:Application Number: JP20100009189