TABLETS HAVING SITE AND TIME CONTROLLED RELEASE OF GASTROINTESTINAL GLUCOCORTICOIDS

PROBLEM TO BE SOLVED: To provide a pharmaceutical formulation having a reproducible site and time controlled release of glucocorticoids regardless of food intake by patient, particularly at a desired site in the intestine. SOLUTION: The solution is given by the pharmaceutical formulation having site...

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Bibliographic Details
Main Author SCHAEFFLER ACHIM
Format Patent
LanguageEnglish
Published 04.03.2010
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a pharmaceutical formulation having a reproducible site and time controlled release of glucocorticoids regardless of food intake by patient, particularly at a desired site in the intestine. SOLUTION: The solution is given by the pharmaceutical formulation having site- and time-controlled releasing action of glucocorticoid which is composed of (a) a core having at least one glucocorticoid which rapidly releases glucocorticoid by contact of the core with gastrointestinal juice and having at least one swellable adjuvant; and (b) a compression molded inactive coating, which coating substantially controls the release of glucocorticoid for a predetermined period after administration of the formulation. COPYRIGHT: (C)2010,JPO&INPIT
Bibliography:Application Number: JP20090269373