COATED PARTICULATE CONTAINING PROTON PUMP INHIBITOR
PROBLEM TO BE SOLVED: To provide a coated particulate for an orally disintegrating tablet containing a benzimidazole proton pump inhibitor, which has good drug release characteristics and can be produced with a good yield, and to provide an orally disintegrating tablet of a benzimidazole proton pump...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
05.11.2009
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Subjects | |
Online Access | Get full text |
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Abstract | PROBLEM TO BE SOLVED: To provide a coated particulate for an orally disintegrating tablet containing a benzimidazole proton pump inhibitor, which has good drug release characteristics and can be produced with a good yield, and to provide an orally disintegrating tablet of a benzimidazole proton pump inhibitor having good storage stability. SOLUTION: The coated particulate is obtained by coating a drug layer containing a benzimidazole proton pump inhibitor and a crospovidone fine powder having an average particle size of 3-10 μm on a spherical crystalline cellulose particle and then coating an inert interlayer and an enteric coating layer. The orally disintegrating tablet includes the coated particulate. COPYRIGHT: (C)2010,JPO&INPIT |
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AbstractList | PROBLEM TO BE SOLVED: To provide a coated particulate for an orally disintegrating tablet containing a benzimidazole proton pump inhibitor, which has good drug release characteristics and can be produced with a good yield, and to provide an orally disintegrating tablet of a benzimidazole proton pump inhibitor having good storage stability. SOLUTION: The coated particulate is obtained by coating a drug layer containing a benzimidazole proton pump inhibitor and a crospovidone fine powder having an average particle size of 3-10 μm on a spherical crystalline cellulose particle and then coating an inert interlayer and an enteric coating layer. The orally disintegrating tablet includes the coated particulate. COPYRIGHT: (C)2010,JPO&INPIT |
Author | UETSUKI KENJI KANAI KYOHEI HIZAKI MASAYA |
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RelatedCompanies | SAWAI PHARMACEUTICAL CO LTD |
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Snippet | PROBLEM TO BE SOLVED: To provide a coated particulate for an orally disintegrating tablet containing a benzimidazole proton pump inhibitor, which has good drug... |
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Title | COATED PARTICULATE CONTAINING PROTON PUMP INHIBITOR |
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