HETEROARYL UREA DERIVATIVE USEFUL FOR INHIBITING CHK1

PROBLEM TO BE SOLVED: To provide substituted urea compounds useful in treatment of diseases and conditions related to DNA damage or lesions in DNA replication. SOLUTION: A compound represented by formula (I) is provided. Pharmaceutical compositions comprising the compound or a pharmaceutically permi...

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Main Authors OOI HUA CHEE, THORSETT EUGENE D, STAPPENBECK FRANK, COOK ADAM WADE, RUDOLPH ALEXANDER, DIAZ FRANK, GAUDINO JOHN JOSEPH, FISHER KIMBA L, FAROUZ FRANCINE S, HOLCOMB RYAN C, KESICKI EDWARD A
Format Patent
LanguageEnglish
Published 08.10.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract PROBLEM TO BE SOLVED: To provide substituted urea compounds useful in treatment of diseases and conditions related to DNA damage or lesions in DNA replication. SOLUTION: A compound represented by formula (I) is provided. Pharmaceutical compositions comprising the compound or a pharmaceutically permissible salt, and a pharmaceutically permissible diluent or carrier, are also provided. COPYRIGHT: (C)2010,JPO&INPIT
AbstractList PROBLEM TO BE SOLVED: To provide substituted urea compounds useful in treatment of diseases and conditions related to DNA damage or lesions in DNA replication. SOLUTION: A compound represented by formula (I) is provided. Pharmaceutical compositions comprising the compound or a pharmaceutically permissible salt, and a pharmaceutically permissible diluent or carrier, are also provided. COPYRIGHT: (C)2010,JPO&INPIT
Author KESICKI EDWARD A
OOI HUA CHEE
STAPPENBECK FRANK
FISHER KIMBA L
COOK ADAM WADE
RUDOLPH ALEXANDER
FAROUZ FRANCINE S
THORSETT EUGENE D
GAUDINO JOHN JOSEPH
DIAZ FRANK
HOLCOMB RYAN C
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– fullname: DIAZ FRANK
– fullname: GAUDINO JOHN JOSEPH
– fullname: FISHER KIMBA L
– fullname: FAROUZ FRANCINE S
– fullname: HOLCOMB RYAN C
– fullname: KESICKI EDWARD A
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Snippet PROBLEM TO BE SOLVED: To provide substituted urea compounds useful in treatment of diseases and conditions related to DNA damage or lesions in DNA replication....
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title HETEROARYL UREA DERIVATIVE USEFUL FOR INHIBITING CHK1
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