HETEROARYL UREA DERIVATIVE USEFUL FOR INHIBITING CHK1

PROBLEM TO BE SOLVED: To provide substituted urea compounds useful in treatment of diseases and conditions related to DNA damage or lesions in DNA replication. SOLUTION: A compound represented by formula (I) is provided. Pharmaceutical compositions comprising the compound or a pharmaceutically permi...

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Main Authors OOI HUA CHEE, THORSETT EUGENE D, STAPPENBECK FRANK, COOK ADAM WADE, RUDOLPH ALEXANDER, DIAZ FRANK, GAUDINO JOHN JOSEPH, FISHER KIMBA L, FAROUZ FRANCINE S, HOLCOMB RYAN C, KESICKI EDWARD A
Format Patent
LanguageEnglish
Published 08.10.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide substituted urea compounds useful in treatment of diseases and conditions related to DNA damage or lesions in DNA replication. SOLUTION: A compound represented by formula (I) is provided. Pharmaceutical compositions comprising the compound or a pharmaceutically permissible salt, and a pharmaceutically permissible diluent or carrier, are also provided. COPYRIGHT: (C)2010,JPO&INPIT
Bibliography:Application Number: JP20090122107