ANTIBODY MOLECULE HAVING SPECIFICITY FOR HUMAN TUMOR NECROSIS FACTOR ALPHA AND USE THEREOF

• Main Authors: BROWN DEREK T, CHAPMAN ANDREW P, CHARLES WEIR ANDREW NEIL, POPPLEWELL ANDREW G, KING DAVID J, ATHWAL DILJEET S
• Format: Patent
• Language: English
• Published: 06.08.2009
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide an antibody molecule having specificity for an antigenic determinant group of human tumor necrosis factor (TNF α), and to provide a therapeutic use of the antibody molecule and a method for producing the antibody molecule. SOLUTION: The antibody molecule containing a...