FUMARIC ACID DERIVATIVE AS NF-KAPPAB INHIBITOR

PROBLEM TO BE SOLVED: To provide a medicinal composition for treating diseases affected by NF-kappaB. SOLUTION: One or more fumaric acid derivative is used to prepare a therapeutic medicinal composition for diseases affected by NF-kappaB. The fumaric acid derivative is selected from a group consisti...

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Bibliographic Details
Main Authors JOSHI RAJENDRA K, PETZELBAUER PETER, STREBEL HANS-PETER
Format Patent
LanguageEnglish
Published 09.04.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a medicinal composition for treating diseases affected by NF-kappaB. SOLUTION: One or more fumaric acid derivative is used to prepare a therapeutic medicinal composition for diseases affected by NF-kappaB. The fumaric acid derivative is selected from a group consisting of free acids of dialkyl fumarate and monoalkyl fumarate, which may be optionally substituted, salts of the free acids, and mixtures thereof, concretely, one or more selected from a group consisting of dimethyl fumarate, diethyl fumarate, methyl ethyl fumarate, monomethyl fumarate, monoethyl fumarate, calcium methyl fumarate, calcium ethyl fumarate, magnesium methyl fumarate, magnesium ethyl fumarate, zinc methyl fumarate, zinc ethyl fumarate, iron methyl fumarate and iron ethyl fumarate, and mixtures thereof. COPYRIGHT: (C)2009,JPO&INPIT
Bibliography:Application Number: JP20080290821