DRUGS, FOODS, DRINKS OR COSMETICS CONTAINING HISTAMINE-RELEASE INHIBITORS OR LEUKOTRIENE-RELEASE INHIBITORS, CONTAINING NARINGENIN CHALCON AS ACTIVE INGREDIENT

• Main Authors: OBATA AKIO, KANAMORI TOMOKO, YAMAMOTO DAICHI, SAITO MINORU, YAMAGUCHI NORIO, TSUJI RYOHEI
• Format: Patent
• Language: English
• Published: 20.11.2008
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

PROBLEM TO BE SOLVED: To provide novel histamine-release inhibitors or leukotriene-release inhibitors; and drugs, foods, drinks or cosmetics comprising the same. SOLUTION: Disclosed are new histamine-release inhibitors or leukotriene-release inhibitors comprising naringenin chalcon or a salt thereof as an active ingredient, and drugs, foods, drinks or cosmetics comprising the inhibitors. The histamine-release inhibitors or leukotriene-release inhibitors are effective as various antiallergic disorder preventative and therapeutic drugs, and anti-inflammatory medications. Further, since the histamine-release inhibitors or the leukotriene-release inhibitors inhibit release of histamine from mast cells in I type allergic reaction, they are effective especially for preventing and treating atopic dermatitis, allergic rhinitis, pollinosis, or allergic asthma resulting from the release of histamine. COPYRIGHT: (C)2009,JPO&INPIT