PEGYLATED ION CHANNEL MODULATING COMPOUND

PROBLEM TO BE SOLVED: To provide a polyethylene glycolated (PEGylated) ion channel modulating compound that meets the requirement of identification of new antiarrhythmic treatment in both of ventricular arrhythmia and atrial arrhythmia. SOLUTION: This invention is a PEGylated derivative of the ion c...

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Main Authors PLOUVIER BERTRAND M C, CHOU DOUG TA HUANG, CHOI LEWIS SIU LEUNG, EZRIN ALAN M, CHEU ELIZABETH L S, YIFRU AREGAHEGN, DAVIDOFF ALLEN W, JUNG GRACE
Format Patent
LanguageEnglish
Published 18.09.2008
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:PROBLEM TO BE SOLVED: To provide a polyethylene glycolated (PEGylated) ion channel modulating compound that meets the requirement of identification of new antiarrhythmic treatment in both of ventricular arrhythmia and atrial arrhythmia. SOLUTION: This invention is a PEGylated derivative of the ion channel modulating compound having one or more of the PEGylated parts connected to the ion channel modulating compound. In one embodiment, the PEG part is connected via linker to the ion channel modulating compound. The compound also can be connected to the PEG part by substituting any atomic valence of the compound bonded to the PEG part. COPYRIGHT: (C)2008,JPO&INPIT
Bibliography:Application Number: JP20080088708