PIPERIDINE AND PYRROLIDINE

PROBLEM TO BE SOLVED: To provide a new piperidine derivative and a new pyrrolidine derivative each effective for treating diabetes. SOLUTION: The new piperidine compound and the new pyrrolidine compound each having specific substituents are provided, wherein, for example, the substituents include at...

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Bibliographic Details
Main Authors KIRK OLE, LUNDGREN KARSTEN
Format Patent
LanguageEnglish
Published 13.03.2008
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:PROBLEM TO BE SOLVED: To provide a new piperidine derivative and a new pyrrolidine derivative each effective for treating diabetes. SOLUTION: The new piperidine compound and the new pyrrolidine compound each having specific substituents are provided, wherein, for example, the substituents include at least three free-type or protective-type hydroxy groups. Specifically, an example of these compounds is (3R, 4R, 5R)-3,4-dihydroxy-5-hydroxymethylpiperidine. This compound is active as an inhibitor for glucose formation from the liver, thus being usable for dealing with elevated plasma glucose levels in diabetes. COPYRIGHT: (C)2008,JPO&INPIT
Bibliography:Application Number: JP20070267684