METHOD FOR EVALUATION OF DISTENSION STIMULATION-MEDIATED MELANOGENESIS CONTROLLING SUBSTANCE
PROBLEM TO BE SOLVED: To provide a means for evaluating the effect of a test substance on distension stimulation-mediated melanogenesis. SOLUTION: The invention provides a method for the evaluation of a distension stimulation-mediated melanogenesis controlling substance containing a step to culture...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
14.02.2008
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Subjects | |
Online Access | Get full text |
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Summary: | PROBLEM TO BE SOLVED: To provide a means for evaluating the effect of a test substance on distension stimulation-mediated melanogenesis. SOLUTION: The invention provides a method for the evaluation of a distension stimulation-mediated melanogenesis controlling substance containing a step to culture a melanocyte in the presence of the test substance under the load of distension stimulation, a step to determine the quantity of produced melanine, and a step to compare the determined quantity of melanine with the quantity of melanine produced by melanocyte cultured under the load of distension stimulation in the absence of the test substance; and a method for screening a speck-formation inhibiting substance by subjecting the test substance to the evaluation method and screening the test substance as the speck-formation inhibiting substance. COPYRIGHT: (C)2008,JPO&INPIT |
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Bibliography: | Application Number: JP20060203324 |